chorionic mature intermediate villus

mature intermediate villus

A slender branch of a chorionic stem villus. A chorionic mature intermediate villus lacks fetal arterioles and venules in the stroma, which is composed of slender fetal capillaries embedded into a loose connective tissue that is rich in cells but poor in fibers. It exhibits a diameter ranging from 60 to about 100 μm.

Tipo Organ
Estrutura pai chorionic floating villus
Nome latino mature intermediate villus

Perguntas frequentes

What is a chorionic mature intermediate villus?
A chorionic mature intermediate villus is a slender intermediate branch of the villous tree that connects chorionic stem villi to terminal villi. It is a cylindrical structure with a diameter of approximately 60 to 100 micrometers, characterized by a loose connective tissue stroma rich in cells but poor in fibers, containing slender fetal capillaries but lacking fetal arterioles and venules.
How does the mature intermediate villus differ from the immature intermediate villus?
Immature intermediate villi are bulbous, edematous precursor structures that appear early in pregnancy and serve as precursors of stem villi. Mature intermediate villi, by contrast, are slender branches found from the second trimester onward and serve as the conduit for vascular and nutritional supply to the terminal villi. Mature intermediate villi contain a loose, cellular stroma with peripheral capillaries but no arterioles or venules, unlike immature intermediate villi which have a myxoid stroma.
What is the functional role of mature intermediate villi in the placenta?
Mature intermediate villi serve primarily as the branching framework from which terminal villi proliferate. They provide a conduit for the fetal capillaries between the larger vessels of stem villi and the highly capillarized terminal villi where active exchange occurs. The mature intermediate villi also contribute to the total exchange surface area of the placenta.
What does the stroma of a mature intermediate villus contain?
The stroma of a chorionic mature intermediate villus is loose connective tissue rich in cells (fibroblasts and macrophages/Hofbauer cells) but poor in collagen fibers, giving it a relatively loose appearance. Slender fetal capillaries run through this stroma, and unlike the stem villous stroma, there are no arterioles or venules in the stroma of mature intermediate villi.
How are mature intermediate villi related to placental dysfunction?
Deficiency of mature intermediate villi is associated with abnormal placental development. Inadequate proliferation of mature intermediate villi limits the formation of terminal villi and reduces the exchange surface area. This pattern, sometimes called villous hypoplasia or distal villous immaturity, is associated with fetal growth restriction and may be seen in conditions such as preeclampsia, maternal diabetes, and chromosomal abnormalities.

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Data sources: Terminologia Anatomica, Foundational Model of Anatomy, Wikidata.