lymph node

lymph gland

Any of the rounded masses of lymphoid tissue that are surrounded by a capsule of connective tissue, are distributed along the lymphatic vessels, and contain numerous lymphocytes which filter the flow of lymph.

类型 Bone
身体系统 Lymphatic/Immune
上级结构 immune organ
拉丁名称 lymph gland
FMA ID 5034

常见问题

What is the internal anatomy of a lymph node?
Lymph nodes are encapsulated by a fibrous capsule from which trabeculae extend inward. The outer cortex contains follicles (B cell zones) with germinal centers during immune responses. The inner paracortex is T cell-rich. The medulla contains medullary cords (antibody-secreting plasma cells) and sinuses draining to the efferent lymphatic vessel at the hilum.
How do lymph nodes filter lymph?
Lymph enters lymph nodes through multiple afferent lymphatic vessels and percolates through a network of subcapsular, cortical, and medullary sinuses. Macrophages lining these sinuses phagocytose pathogens, cell debris, and foreign particles, while lymphocytes sample antigens to initiate adaptive immune responses.
Why do lymph nodes swell during infection?
Lymph node enlargement (lymphadenopathy) occurs when lymphocytes rapidly proliferate in response to antigens, filling lymphoid follicles with activated B and T cells. Increased macrophage activity and edema within the node also contribute to swelling, which clinically signals ongoing immune activity or infection.

相关结构

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Data sources: Terminologia Anatomica, Foundational Model of Anatomy, Wikidata.