Liver
Hepar
A large, wedge-shaped organ occupying the right hypochondriac and epigastric regions of the abdomen. It is divided into right and left lobes by the falciform ligament. The porta hepatis on the inferior surface is where the hepatic artery, portal vein, and bile duct enter and exit.
Function
The largest internal organ, performing over 500 metabolic functions including bile production, detoxification, protein synthesis (albumin, clotting factors), glycogen storage, and drug metabolism.
Clinical Significance
Cirrhosis results from chronic liver disease (alcohol, hepatitis). Hepatocellular carcinoma is a primary liver cancer. Hepatitis B and C are major global health concerns. Liver transplantation is performed for end-stage liver disease.
Frequently Asked Questions
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Related Structures
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