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blood brain barrier

BBB

The blood brain barrier is a cell layer of lining cells that separates the central nervous system from the bloodstream. It may be constituted by endothelial cells or by glial cells, and comparative evidence indicates that an endothelial barrier may have arisen independently several times during evolution. That variation is documented across fishes: in bichir and lungfish the barrier is formed by brain endothelial cells, whereas in sturgeon it is formed by a complex perivascular glial sheath in which no tight junctions have been detected. The barrier is therefore defined by its separating function rather than by a single cellular architecture. Two subordinate structures are recorded beneath this entry, and it is classified within the nervous system as a cell layer.

Cell layer consisting of lining cells that separates the central nervous system and the bloodstream. The BBB may consist of endothelial cells or glial cells. An endothelial barrier may have arisen independently several times during evolution. In bichir and lungfish the barrier is formed by brain endothelial cells, while in sturgeon it is formed by a complex perivascular glial sheath, but with no detectable tight junctions.

On this page
Type Organ
Body System Nervous
Parent Structure cell layer
Latin Name BBB

Frequently Asked Questions

What is the blood brain barrier?

Cell layer consisting of lining cells that separates the central nervous system and the bloodstream. The BBB may consist of endothelial cells or glial cells. An endothelial barrier may have arisen independently several times during evolution. In bichir and lungfish the barrier is formed by brain end

What body system is the blood brain barrier part of?

The blood brain barrier is part of the Nervous.

What is the Latin name for the blood brain barrier?

The Latin name for the blood brain barrier is BBB.

References

  1. UBERON — UBERON:0000120 Cross-species anatomy ontology (EMBL-EBI Ontology Lookup Service)
  2. Wikipedia — blood brain barrier Encyclopedia article (verified cross-reference)

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Educational Disclaimer

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Data sources: Terminologia Anatomica, Foundational Model of Anatomy, Wikidata.