islet of Langerhans
island of Langerhans
The clusters of hormone-producing cells that are scattered throughout the pancreas.
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| Тип | Gland |
| Система органов | Endocrine |
| Родительская структура | cell cluster |
| Латинское название | island of Langerhans |
| FMA ID | 16016 |
Frequently Asked Questions
What are the main cell types found in the islets of Langerhans?
The islets contain several hormone-secreting cell types: alpha cells (glucagon), beta cells (insulin, the most abundant type), delta cells (somatostatin), PP cells (pancreatic polypeptide), and epsilon cells (ghrelin). Each cell type regulates distinct metabolic functions.
How do islets of Langerhans differ from the exocrine pancreas?
Islets are endocrine structures that secrete hormones directly into the bloodstream, comprising about 1-2% of the pancreatic mass. The surrounding exocrine pancreas produces digestive enzymes secreted into the duodenum via ducts.
What happens to islets of Langerhans in type 1 diabetes?
In type 1 diabetes, the immune system attacks and destroys the insulin-producing beta cells within the islets of Langerhans. This autoimmune destruction results in absolute insulin deficiency, requiring lifelong insulin therapy.
References
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Educational Disclaimer
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider for medical decisions.
Data sources: Terminologia Anatomica, Foundational Model of Anatomy, Wikidata.
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