| Fungsi |
Produces steroid hormones (cortisol, aldosterone, androgens) from the cortex and catecholamines (epinephrine, norepinephrine) from the medulla. Essential for stress response, metabolism, blood pressure regulation, and immune function. |
Produces thyroid hormones (T3 and T4) that regulate metabolic rate, protein synthesis, and sensitivity to other hormones. Also produces calcitonin, which helps regulate calcium homeostasis. |
| Signifikansi Klinis |
Addison's disease is primary adrenal insufficiency. Cushing's syndrome results from excess cortisol. Pheochromocytoma is a catecholamine-producing tumor of the medulla. Adrenal crisis is an acute life-threatening condition requiring emergency treatment. |
Hypothyroidism (Hashimoto's thyroiditis) and hyperthyroidism (Graves' disease) are common endocrine disorders. Thyroid nodules and goiter affect millions. Thyroid cancer, while relatively uncommon, has excellent prognosis when treated early. Thyroidectomy risks … |