chorionic immature intermediate villus

immature intermediate villus

A bulbous, immature chorionic villus that is formed of loose connective tissue with few fetal vessels. A chorionic immature intermediate villus develops from a chorionic mesenchymal villus, and is the forerunner of a chorionic stem villus.

Type Vessel
Structure parente chorionic villus
Nom latin immature intermediate villus

Questions fréquentes

What is a chorionic immature intermediate villus?
A chorionic immature intermediate villus is a bulbous, edematous type of chorionic villus with loose connective tissue and few fetal vessels. It develops from a chorionic mesenchymal villus and serves as the precursor of a chorionic stem villus, representing an early stage in the maturation of the villous tree.
When are immature intermediate villi normally present in the placenta?
Immature intermediate villi are the predominant villous type during the first and second trimesters of normal pregnancy. In the third trimester, they persist in only small numbers in the centers of villous lobules, where they continue to generate new mesenchymal villi as part of ongoing placental growth. Their persistence beyond 36 weeks in large numbers is considered abnormal.
What distinguishes an immature intermediate villus from a mature intermediate villus?
Immature intermediate villi are bulbous with a myxoid (edematous, mucoid) stroma rich in reticular fibers but few collagen fibers, and contain relatively few fetal vessels. Mature intermediate villi are slender, with a cellular loose stroma, and contain numerous peripheral capillaries. Immature intermediate villi are precursors of stem villi; mature intermediate villi are precursors of terminal villi.
What is the significance of excessive immature intermediate villi in the third trimester?
When immature intermediate villi predominate in the third trimester in an abnormal pattern called distal villous immaturity (or delayed villous maturation), it indicates failure of normal placental maturation. This condition is associated with diabetes mellitus (particularly poorly controlled gestational and pregestational diabetes) and with adverse perinatal outcomes including fetal distress, stillbirth, and neonatal hypoglycemia.
How do immature intermediate villi contribute to placental growth?
Immature intermediate villi act as growth centers of the villous tree. Proliferating mesenchymal cells within their stroma produce new mesenchymal villi by sprouting, which then mature into either more stem villi or mature intermediate villi and terminal villi. This continuous branching process throughout pregnancy allows the placenta to expand its exchange capacity to meet the growing metabolic demands of the fetus.

Structures associées

mucus body coating mucous body coating mucus cocoon mucous cocoon Mullerian duct ductus paramesonephricus multi cell part structure cell part cluster multicellular anatomical structure multicellular structure multilaminar epithelium laminated epithelium multi-tissue structure multi-tissue structures multi-unit eye

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Data sources: Terminologia Anatomica, Foundational Model of Anatomy, Wikidata.