chorioallantoic membrane

chorioallantois

The chorioallantoic membrane is a vascular membrane found in eggs of some amniotes, such as birds and reptiles. It is formed by the fusion of the mesodermal layers of two developmental structures: the allantois and the chorion. Three different layers compose the chorioallantoic membrane; these are called the chorionic epithelium, the mesenchyme and the allantoic epithelium. Blood capillaries and sinuses are found between epithelial cells of the chorionic layer, allowing close contact (within 0.2 N<m) with air found in pores of the shell membrane of the egg. As a result, the chorioallantoic membrane allows exchange of gases, such as oxygen, to developing embryos. During embryonic development of birds, the chorioallantoic membrane also plays an essential role in bone formation by transporting calcium into the embryo from the eggshell. Chorioalloantoic membranes from developing chicken eggs are routinely used in biological and biomedical research to investigate development, angiogenesis, tumors, and to propagate and investigate viruses or helminths.

Tipo Bone
Estructura principal extraembryonic membrane
Nombre latino chorioallantois

Preguntas frecuentes

What is the chorioallantoic membrane?
The chorioallantoic membrane (CAM) is a highly vascular extraembryonic membrane found in amniote eggs (birds and reptiles). It forms by fusion of the allantois and the chorion and serves as the primary respiratory organ of the developing embryo within the eggshell.
How does the chorioallantoic membrane form?
The CAM forms when the allantois (an outgrowth of the embryonic hindgut) grows outward and fuses with the chorion (the outer extraembryonic membrane). This fusion creates a trilaminar structure with a dense capillary network just beneath the eggshell membrane.
What are the three layers of the chorioallantoic membrane?
The chorioallantoic membrane consists of three layers: the chorionic epithelium (outermost, adjacent to the eggshell membrane), the mesodermal stroma (containing the capillary network), and the allantoic epithelium (innermost, lining the allantoic cavity).
What is the primary function of the chorioallantoic membrane?
The CAM functions primarily in gas exchange—oxygen diffuses from air through the porous eggshell into the capillary-rich CAM, while carbon dioxide and water vapor diffuse outward. It also stores metabolic waste products (uric acid) in the allantoic cavity.
What is the scientific use of the chorioallantoic membrane?
The CAM of fertilized chicken eggs is widely used in biomedical research as an in vivo model for studying angiogenesis (blood vessel formation), tumor growth, and drug testing because of its accessibility, rich vascularity, and immunological immaturity.

Estructuras relacionadas

mucus body coating mucous body coating mucus cocoon mucous cocoon Mullerian duct ductus paramesonephricus multi cell part structure cell part cluster multicellular anatomical structure multicellular structure multilaminar epithelium laminated epithelium multi-tissue structure multi-tissue structures multi-unit eye

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Data sources: Terminologia Anatomica, Foundational Model of Anatomy, Wikidata.