Liver vs Spleen

Property Liver Spleen
Latin Name Hepar Lien
Type Organ Organ
Body System Digestive Lymphatic/Immune
Body Region Abdomen Abdomen
Function The largest internal organ, performing over 500 metabolic functions including bile production, detoxification, protein synthesis (albumin, clotting factors), glycogen storage, and drug metabolism. The largest lymphoid organ, filtering blood and removing old or damaged red blood cells. Stores platelets and monocytes. Produces antibodies and mounts immune responses against blood-borne pathogens.
Clinical Significance Cirrhosis results from chronic liver disease (alcohol, hepatitis). Hepatocellular carcinoma is a primary liver cancer. Hepatitis B and C are major global health concerns. Liver transplantation is performed for end-stage … Splenic rupture from blunt abdominal trauma is a surgical emergency. Splenomegaly occurs in various hematologic and infectious conditions. Post-splenectomy patients are at increased risk for encapsulated bacterial infections.
FMA ID 7197 7196