Thymus

Thymus

A bilobed organ located in the anterior superior mediastinum, posterior to the sternum and anterior to the great vessels. It is largest during puberty (30-40g) and gradually involutes with age, being replaced by adipose tissue. Each lobe has a cortex (dense with immature T cells) and medulla (Hassall's corpuscles).

النوع Gland
جهاز الجسم Lymphatic/Immune
منطقة الجسم Thorax
الاسم اللاتيني Thymus
FMA ID 9607

الوظيفة

The primary lymphoid organ responsible for T-lymphocyte maturation and selection. T cells develop from bone marrow precursors and undergo positive and negative selection in the thymus to become immunocompetent while avoiding autoimmunity.

الأهمية السريرية

Myasthenia gravis is associated with thymic hyperplasia or thymoma; thymectomy can be therapeutic. DiGeorge syndrome involves thymic aplasia and severe T cell immunodeficiency. The thymus involutes with age, contributing to age-related immune decline (immunosenescence).

الأسئلة الشائعة

What is the Thymus?
A bilobed organ located in the anterior superior mediastinum, posterior to the sternum and anterior to the great vessels. It is largest during puberty (30-40g) and gradually involutes with age, being replaced by adipose tissue. Each lobe has a cortex (dense with immature T cells) and medulla (Hassal
What is the function of the Thymus?
The primary lymphoid organ responsible for T-lymphocyte maturation and selection. T cells develop from bone marrow precursors and undergo positive and negative selection in the thymus to become immunocompetent while avoiding autoimmunity.
What body system is the Thymus part of?
The Thymus is part of the Lymphatic/Immune.
What conditions affect the Thymus?
Myasthenia gravis is associated with thymic hyperplasia or thymoma; thymectomy can be therapeutic. DiGeorge syndrome involves thymic aplasia and severe T cell immunodeficiency. The thymus involutes with age, contributing to age-related immune decline (immunosenescence).
Where is the Thymus located?
The Thymus is located in the Thorax region of the body.

البنى ذات الصلة

إخلاء المسؤولية الطبية

هذا المحتوى لأغراض تعليمية وإعلامية فقط. لا يُقصد به أن يكون بديلاً عن المشورة الطبية المهنية أو التشخيص أو العلاج. استشر دائماً طبيبك أو مزود الرعاية الصحية المؤهل الآخر بشأن أي أسئلة قد تكون لديك بخصوص حالة طبية. لا تتجاهل أبداً المشورة الطبية المهنية أو تتأخر في طلبها بسبب شيء قرأته على هذا الموقع.